| Award | Nominee | Season | |
|---|---|---|---|
| Golden Globe Award for Best Actor – Television Series Drama (1998) | Dylan McDermott | - | winner |
| Golden Globe Award for Best Television Series - Drama (1998) | - | winner | |
| Primetime Emmy Award for Outstanding Drama Series (1998) | Season 2 | winner | |
| Golden Globe Award for Best Actor – Television Series Drama (1999) | Dylan McDermott | - | shortlisted |
| Golden Globe Award for Best Television Series - Drama (1999) | - | shortlisted | |
| Primetime Emmy Award for Outstanding Drama Series (1999) | Season 3 | winner | |
| Primetime Emmy Award for Outstanding Lead Actor in a Drama Series (1999) | Dylan McDermott | - | shortlisted |
| Golden Globe Award for Best Actor – Television Series Drama (2000) | Dylan McDermott | - | shortlisted |
| Golden Globe Award for Best Television Series - Drama (2000) | - | shortlisted | |
| Primetime Emmy Award for Outstanding Drama Series (2000) | Season 4 | shortlisted | |
| Primetime Emmy Award for Outstanding Drama Series (2001) | Season 5 | shortlisted | |
| Primetime Emmy Award for Outstanding Lead Actor in a Drama Series (2004) | James Spader | - | winner |