| Award | Nominee | Season | |
|---|---|---|---|
| Golden Globe Award for Best Actor – Television Series Drama (2004) | James Spader | - | shortlisted |
| Primetime Emmy Award for Outstanding Lead Actor in a Drama Series (2005) | James Spader | - | winner |
| Primetime Emmy Award for Outstanding Drama Series (2007) | Season 3 | shortlisted | |
| Primetime Emmy Award for Outstanding Lead Actor in a Drama Series (2007) | James Spader | - | winner |
| Primetime Emmy Award for Outstanding Drama Series (2008) | Season 4 | shortlisted | |
| Primetime Emmy Award for Outstanding Lead Actor in a Drama Series (2008) | James Spader | - | shortlisted |